Monthly Archives: August 2017

Scientists have eliminated HIV in mice using CRISPR

https://techcrunch.com/2017/05/03/scientists-have-eliminated-hiv-in-mice-using-crispr/

“An important breakthrough has been made in the eradication of AIDs. Scientists have found they can successfully snip out the HIV virus from mouse cells using CRISPR/Cas9 technology.

Right now patients with the deadly virus must use a toxic concoction of anti-retroviral medications to suppress the virus from replicating. However, CRISPR/Cas9 can be programmed to chop out any genetic code in the body with scissor-like precision, including, possibly, all HIV-1 DNA within the body. And if you cut out the DNA, you stop the virus from being able to make copies of itself.

First published in the journal Molecular Therapy, the team is the first to show HIV can be completely annihilated from the body using CRISPR. And with impressive effect. After just one treatment, scientists were able to show the technique had successfully removed all traces of the infection within mouse organs and tissue.

However, it’s not a permanent solution and it’s still early days for the crew — the study merely builds on a previous proof-of-concept study they conducted last year and the technique has only been used on mice so far. But, should the scientists be able to replicate their findings, the technique could move to human trials in the future.”

“The next stage would be to repeat the study in primates, a more suitable animal model where HIV infection induces disease, in order to further demonstrate elimination of HIV-1 DNA in latently infected T cells and other sanctuary sites for HIV-1, including brain cells,” said co-author of the study Dr. Khalili in a statement. “Our eventual goal is a clinical trial in human patients.”

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Curso de Posgrado sobre Modelado Molecular

Modelado 2Modelado

Química Viva: Nuevo número

Invitamos a visitar la página de la importante revista argentina: Química Viva que en su nuevo número publica los siguientes artículos:

Socios de la resistencia a antibióticos Beatriz S. Méndez

◢ Sobre hombros de gigantes Eduardo Braun Menéndez: un grande de la ciencia y la universidad argentinas  Guillermo Jaim Etcheverry

◢ Revisión La complejidad de lo simple: la célula bacterianaMercedes Berlanga y Ricardo Guerrero

◢ Trabajos de investigaciónLos insecticidas organofosforados metilazinfos y clorpirifos y el carbamato carbaril producen un incremento de los niveles de espermidina en las gónadas del gasterópodo de agua dulce Planorbarius corneus

Luis Claudio Cacciatore, Noemi Rosario Verrengia Guerrero, Adriana Cristina Cochón

Evaluación de la actividad antimicrobiana de los extractos de las hojas de Colubrina arborescens (Mill.) Sarg.

Mijail Mijares Bullaín Galardis, Dania Santana Machado, Willian Corría Sánchez

◢ Trabajo de educación La célula modelizada: una reflexión necesaria en el ámbito de la enseñanza Natalia Ospina Quintero y Lydia Galagovsky

 

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Taller sobre Microscopía Electrónica de Barrido

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Jornada: Microorganismos Probióticos en Alimentos

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Curso de Posgrado: “Avances en nano(bio)materiales y su aplicación en biomedicina”

Curso de Doctorado

Córdoba, 25 al 29 de septiembre de 2017

Directoras: Prof. Dra. Paulina Laura Páez y Prof. Dra. María Gabriela Paraje.

Horario: 9 a 18 hs.          Lugar: en Auditorio FCQ (UNC), Edificio Integrador,

Ciudad Universitaria (Córdoba).

 

Organiza: Departamento de Ciencias Farmacéuticas (FCQ, UNC).

Inscripciones onlinehasta el 4 de septiembre de 2017

Más informaciónDra. Paulina L. Páez. E-mail: plpaez@fcq.unc.edu.ar  

Dra. María G. Paraje. E-mail: paraje@efn.uncor.edu

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Curso Avanzado de Microscopía Confocal de Barrido Láser

IBR Curso